| Hydration Status and Clinical Features in Patients with End-Stage Renal Disease on Regular Hemodialysis |
| Won Ik Jang, M.D., Hong Jin Bae, M.D., Young Rok Ham, M.D., Dong Suk Chang, M.D., Dae Eun Choi, M.D., Ki Ryang Na, M.D., Kang Wook Lee, M.D. and Young Tai Shin, M.D. |
| Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea |
| 원저 : 혈액투석치료를 받는 말기신부전 환자에서 체내 수분분포와 임상상 |
| 장원익, 배홍진, 함영록, 장동석, 최대은, 나기량, 이강욱, 신영태 |
| 충남대학교 의과대학 내과학교실 |
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| Abstract |
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Purpose: Maintenance of the normal hydration state is one of the major purposes of hemodialysis therapy in patients with end-stage renal disease. Overhydration is an important and independent predictor of mortality in patients with end-stage renal disease on regular hemodialysis. BCM (body composition monitor, FMC, Germany) reliably enables quantitative assessment of hydration status and body composition. The aims of this study were to investigate the relationship between hydration status and clinical features and the risk factors of overhydration.
Methods: We measured hydration status and body composition of total 72 patients with end-stage renal disease on regular hemodialysis by BCM from June, 2009 to September, 2009. We also reviewed the clinical characteristics and laboratory findings and comorbidities retrospectively.
Results: The hydration status measured by BCM was correlated well with interdialytic weight gain after 48 hours and 72 hours from last hemodialysis treatment (r=0.42 p<0.001, r=0.38 p<0.01, respectively). There was no statistically significant difference in comorbidities, age, sex, BMI, blood pressure, hypotensive episodes between the patients with overhydrated state (relative hydration status ≥20%) and control patients (relative hydration status <20%). In overhydrated patients, serum iron level was lower than control patients 48 hrs after last hemodialysis (p<0.05).
Conclusion: This cross-sectional study showed that hydration status measured by BCM was correlated well with interdialytic weight gain although there was no significant clinical difference between overhydrated and control patients with end-stage renal disease on regular hemodialysis |
| Key Words:
Body composition, Hemodialysis, ESRD |
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